Robert J. Lefkowitz. wins the 2009 Frontiers of Knowledge Award in Biomedicine


The 2009 BBVA Foundation Frontiers of Knowledge Award in the Biomedicine category goes to Prof. Robert J. Lefkowitz (New York, 1943) for identifying the receptors targeted by around half of todays prescription drugs. Lefkowitz is author of more than 850 research papers that at the time of writing have been cited on over 95000 occasions. His findings have led to the development of numerous drugs for a wide variety of conditions, above all in neurology (Parkinsons disease), cardiology (arterial hypertension) and diabetes.

Thomas Steitz wins Nobel Prize for Chemistry


Nobel Prize winner Thomas Steitz, a Sterling Professor of Molecular Biophysics and Biochemistry at Yale, speaks at a press conference in Woolsey Hall Wednesday afternoon.

Saturated/Unsaturated Fatty Acid Structures


Understanding the chemical structure for saturated and unsaturated (cis and trans) fatty acids. A “fat molecule” is also called a “triglyceride” or “triacylglyceride.” Fatty acids have a polar carboxylic acid “head” and a non-polar hydrocarbon “tail.” Overall, a molecule with a large hydrocarbon chain is more soluble in fats/oils/hydrocarbons (ie. nonpolar solvents). In general, we use the phrase “like dissolves like” to predict the solubility of a compound in a polar or non-polar solvent. A molecule with a very short hydrocarbon chain (vinegar/acetic acid) is more soluble in water; the polar carboxylic acid functional group “wins”. The hypothetical fat molecule that I showed is called a “triglyceride” because the glycerol is esterified with 3 fatty acids.

Thermalin Diabetes wins $250,000 to develop new insulins

Thermalin Diabetes wins $250,000 to develop new insulins
Thermalin Diabetes Inc., the Cleveland start-up that is developing new forms of insulin, has received a $250,000 investment commitment from JumpStart Ventures on the way to a Series A fundraising likely to be completed by the end of May. “It’s the first piece of what I think will be close to $2 million-worth of financing we’re [...]

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Big Pharma Wins Big in Health Care Reform

Big Pharma Wins Big in Health Care Reform
The Republicans look a sour lot this morning, but the pharmaceutical industry, which helps foot the campaign bills of a sizeable chunk of members of both parties, is delighted with the legislation, and with its Democratic friends in the White House and on the Hill.

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