CHIMBRIDS – Chimeras and Hybrids in Comparative European and International Research: Scientific, Ethical, Philosophical and Legal Aspects

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National, European and international concepts and strategies concerning the legal and ethical framework of chimera and hybrid research are still largely missing, even though they are absolutely necessary in order to use the potential of chimera and hybrid research effectively and efficiently for the benefit of science and society. The outcome of the CHIMBRIDS-Project successfully sheds light on the chances and risks of this research and provides legal solutions to existing problems in order to help decision-makers fulfil their tasks in an informed and efficient manner.

This comprehensive volume details the complete results, contributed by 40 scholars from 10 member states of the European Union, Canada, China, Israel, Japan, Switzerland and the US, with descriptive reports of the legal situation in specific countries and in-depth analysis of all scientific, medical, ethical and legal implications of chimera and hybrid research.

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Biomedical Research: How to plan, publish and present it

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This handy book will be an aid to anyone who is tackling BSc, MPhil, MSc and PhD projects and those setting off on the road to their first publication in the field of biomedical literature or writing grant applications, by dealing with all the steps that are necessary for planning, publishing and presenting research. There have been many developments since 1985 when Hawkins’ ‘Research: How to Plan, Speak and Write about it’ was published, not least the use of computerised word processing, graphics and statistics packages, and computerised facilities within libraries. Professor Whimster, has produced a new work which builds on Hawkins’ work and updates and modernises it with the aim of making it more relevant to those operating in today’s research environments.

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Integrating research and development: the emergence of rational drug design in the pharmaceutical industry

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This digital document is a journal article from Studies in History and Philosophy of Biol & Biomed Sci, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Rational drug design is a method for developing new pharmaceuticals that typically involves the elucidation of fundamental physiological mechanisms. It thus combines the quest for a scientific understanding of natural phenomena with the design of useful technology and hence integrates epistemic and practical aims of research and development. Case studies of the rational design of the cardiovascular drugs propranolol, captopril and losartan provide insights into characteristics and conditions of this integration. Rational drug design became possible in the 1950s when theoretical knowledge of drug-target interaction and experimental drug testing could interlock in cycles of mutual advancement. The integration does not, however, diminish the importance of basic research for pharmaceutical development. Rather, it can be shown that still in the 1990s, linear processes of innovation and the close combination of practical and epistemic work were interdependent.

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Sourcebook of Models for Biomedical Research

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The collection of systems represented in the Sourcebook of Models for Biomedical Research reflect the diversity and utility of models that are used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. Some models have the advantage that the reproductive, mitotic, development or aging cycles are rapid compared with those in humans; others are utilized because individual proteins may be studied in an advantageous way and have human homologs. Other organisms are facile to grow in laboratory settings, lend themselves to convenient analyses, have defined genomes or present especially good human models of human or animal disease. The Sourcebook of Models for Biomedical Research is a comprehensive and extensive collection of these important medical parallels. While the entire book is not devoted to the remarkable success of the genomic programs, this work is well represented and indexed within these pages. This volume will be an invaluable resource for pharmaceutical and academic researchers across a wide range of biological fields.

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Human dignity & stemcell research in the EU: ESTOOLS project


In February 2007 EuroNews, the channel of reference on EU-related news, came to the Centre for Stem Cell Biology at Sheffield University in Great Britain to film for a broadcast about the EU’s reconfirmation of stem cell research funding. Professor Peter Andrews leads from Sheffield the EU-funded €12m “ESTOOLS” FP6 Integrated Project involving 19 other European labs, both academic and SMEs. The broadcast went out in March 2007 and highlights the aims of such research ultimately to enable the development of cures for serious illnesses. Titled “Human dignity and stem cell research in the EU”, the programme also explains the range of ethical standpoints within Europe over the fate of surplus human embryonic stem cells created by IVF treatments – a theme of debate between experts and members of the European Parliament, causing divisions within all the political parties. Peter Andrews was joined for the filming at the CSCB by Timothy Kirkhope, the Yorkshire & Humberside member in the EU Parliament and leader of the Conservatives there.