We will present state-of-the-art methods for open surface fluid simulation, developed at the Center for Computational Biomedicine, Imaging and Modeling of Rutgers University. The first is a Marker Level Set method that enables the simulation of both small and large scale fluid dynamics, and our methodology for simulating multiphase boiling phenomena. We will show boiling simulations in 0 and 1-gravity and animations of interaction between animated bodies and liquids, with strong generation of droplets and bubbles. The second method involves the use of meshless finite methods, for the accurate estimation of cardiac strain from MRI-tagged data. These methods, coupled with learning methods allow the accurate analysis of the cardiac motion and the strain-based comparison of different imaging modalities such as ultrasound and MRI. This is joint work with Viorel Mihalef and Xiaoxu Wang. Dr. Dimitris Metaxas is from Rutgers University. Note: Original video was 320×240.