Biopharmaceutics Applications in Drug Development

Product Description

In the last two decades, the discipline of biopharmaceutics has undergone considerable advances, particularly with regard to bioavailability and bioequivalence as they relate to product quality and regulatory standards of approval. Textbooks in the field have not been able to keep up with the growth of current and emerging applications of regulatory aspects of biopharmaceutics.

Biopharmaceutics Applications in Drug Development fills this gap. This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development.

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Hydrogels: Biological Properties and Applications

Product Description

The studies on Biohydrogels have had a rapid, exponential evolution in the last decades. Starting from one of the first applications of hydrogels in surgery, polyvinylalcohol crosslinked with formaldehyde under the trade name of Ivalon, we passed through PolyHema hydrogels as contact lens materials, hydrophilic polyurethanes (HPU), biodegradable hydrogels for both reconstructive surgery and pharmaceutical delivery systems, and finally more recently, one decade old, the thermoreversible and transient network hydrogels. Of course all these classes of hydrogels have been always and continuosly studied, improving their performance and field of applications. Recently, most of them have been used as scaffolds for cells, even stem ones, for regenerative applications (tissue engineering). Nevertheless hydrogels are odd materials and many studies still have to be carried out to fully understand their behaviour from mechanical, physicochemical and biological point of view.

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The Rappaport Family Institute and BioRap Technologies


The Rappaport Institute: www.rappinst.com BioRap Technologies www.bio-rap.com The Rappaport Family Institute for Research in the Medical Sciences was established in 1982 to promote excellence in biomedical research. The Institute supports outstanding researchers from the Technion’s Faculty of Medicine with research funding, laboratory space and access to advanced equipment. During more than two decades of activity, the Institute has established itself as an internationally recognized research center and counts among its members several world-renowned scientists. BioRap Technologies Ltd. was established in 2001 as a private company fully owned by the Rappaport Family Institute for Research in the Medical Sciences, and is located within its facilities. BioRaps goal is to promote innovative research by Rappaport Institute members.

Why is Richard Dawkins left speechless in front of a plain truth ?


“If itcould be demonstrated that any complex organ existed, which could not possibly have been formed by numerous, successive, slight modifications, my theory would absolutely break down. So wrote Charles Darwin in `The Origin of Species`, where he made his theory of evolution public. The theory applied materialist philosophy to nature and challenged the consensus that life on earth is the artifact of the Creator. During the following 150 years, many in the scientific community assumed that Darwin had almost accomplished this task. Today, science demonstrates that they were mistaken. Findings in the last two decades alone have shattered the basis of the theory. Key branches of science, such as paleontology, biochemistry, population genetics, comparative anatomy, and biophysics, indicate one after another that natural laws and chance effects proposed by the theory cannot explain the origin of life. Life turns out to be infinitely more complex than Darwin imagined in his time demonstrating that his theory has absolutely broken down. Links for exploration: www.darwinism-watch.com www.fossil-museum.com www.ambersdenydarwin.com www.evolutiondocumentary.com www.living-fossils.com www.cambriananddarwin.com www.confessionsofevolutionists.com www.oldestmushroom.com www.reptile-fossils.com www.baltic-ambers.com www.thestoneage.org www.darwinismthegreatestlieinhistory.com www.evolutiontale.com www.whatdarwindidnotknow.com www.collapseofatheism.com www.darwinistdishonesty.com www

The REAL Origin of Life.


“If itcould be demonstrated that any complex organ existed, which could not possibly have been formed by numerous, successive, slight modifications, my theory would absolutely break down. So wrote Charles Darwin in `The Origin of Species`, where he made his theory of evolution public. The theory applied materialist philosophy to nature and challenged the consensus that life on earth is the artifact of the Creator. During the following 150 years, many in the scientific community assumed that Darwin had almost accomplished this task. Today, science demonstrates that they were mistaken. Findings in the last two decades alone have shattered the basis of the theory. Key branches of science, such as paleontology, biochemistry, population genetics, comparative anatomy, and biophysics, indicate one after another that natural laws and chance effects proposed by the theory cannot explain the origin of life. Life turns out to be infinitely more complex than Darwin imagined in his time demonstrating that his theory has absolutely broken down. Links for exploration: www.darwinism-watch.com www.fossil-museum.com www.ambersdenydarwin.com www.evolutiondocumentary.com www.living-fossils.com www.cambriananddarwin.com www.confessionsofevolutionists.com www.oldestmushroom.com www.reptile-fossils.com www.baltic-ambers.com www.thestoneage.org www.darwinismthegreatestlieinhistory.com www.evolutiontale.com www.whatdarwindidnotknow.com www.collapseofatheism.com www.darwinistdishonesty.com www